So I used to ride it for a little while and then just stop

So I used to ride it for a little while, and then just stop at a grass verge, let him nibble away a bit, and just talk to him. Eventually, he learnt to relax, and won a couple of races.”Simple as that, then. Find a horse on whom patience and love has been lavished in Jenny Pitman’s style, and you may have found the winner The First Lady herself will not be betting She rarely does. Although her love for horses remains undimmed, her withdrawal from what can be a pretty spiteful game at times seems to have been an altogether Good Thing for Jenny and David.She is writing furiously – a second novel is due out in November – and if she knows she that has been in a race, then the good news is that several hurdles have been successfully negotiated, and she is now in the straight, still galloping, but safely and contentedly.Jenny Pitman’s novel ‘On the Edge’ is published by Macmillan, £16.99. Growing consumption of highly refined starches such as bread and cereals may be the cause of increasingly widespread short-sightedness, according to new research. But high levels of insulin are also known to lead to a drop in levels of “binding protein-3″, which is crucial in the growth process – and to which the eye is particularly sensitive.Loren Cordain, an evolutionary biologist at Colorado State University in Fort Collins, and Jennie Brand Miller, a nutrition scientist at the University of Sydney, told New Scientist magazine that their theory could explain why 30 per cent of people of European descent now suffer from some level of myopia..

This time last year, baby Rhys Evans was struck down with pneumonia and needed a ventilator to breathe. Suffering from a rare inherited disorder that had robbed him of a working immune system, Rhys had to live in an ultra-sterile hospital room cut off from the outside world.
Today, the 18-month-old toddler is like any other little boy of his age – full of mischief and fun, with an insatiable desire to run around whenever he can. He lives at home and shows no signs he was once so ill.Doctors at Great Ormond Street Hospital said yesterday that Rhys was living proof that gene therapy works. Some went so far as to say he has been cured – the first gene therapy patient to receive that accolade in Britain, and only the second gene therapy “cure” worldwide.”We’re very pleased to announce the successful cure of the first patient in the UK by gene therapy,” said Professor Christine Kinnon, director of the Centre of Gene Therapy for Childhood Diseases at the Institute of Child Health in London, who collaborated on treatment.It is rare for doctors to use the “c” word. Cures are meant to be permanent and, although Rhys shows every sign he is now normal, there is still a risk he may relapse, making him once again vulnerable to the opportunistic infections that strike someone with a compromised immune system.Indeed, Adrian Thrasher, the consultant paediatric immunologist at the Great Ormond Street Hospital, who carried out the treatment was more cautious. “I’d like to say that Rhys is cured but we can’t say that,” he said.”Rhys will be followed up for years and years.

Only in the long term will we really be able to compare what we’ve done to Rhys with our other patients who’ve been through more conventional transplant procedures.”The first signs that something was wrong with Rhys came four months after his birth at about the time when his mother, Marie, began to stop breastfeeding. A series of chest infections turned into severe pneumonia, which led to 10 days in an oxygen tent before he was put on a ventilator After a series of tests, the problem was finally identified. Rhys had acquired a defective gene on the x-chromosome – inherited from his mother. It meant he could not produce the vital lymphocytes – a type of white blood cell – essential for his immune system.Medically, the condition is called x-linked severe combined immunodeficiency (XSCID). The more popular name is “baby in the bubble” syndrome, because of the sterile plastic spheres used to protect some babies with the disorder.An analysis of Rhys’s blood showed the few lymphocytes he possessed came from his mother and the supply had been cut off when breastfeeding ended.Marie Evans, 31, remembers the pit of despair she and her husband faced knowing their little boy was so ill She said yesterday: “Life was a bit of a rollercoaster. One day we could be up and the other day we could be down.”Mark, her husband, gave up his job to care for Rhys and he suffered badly from depression and anxiety Mr Evans said: “If you’d seen how bad he was. He was skin and bone, too weak to hold his head up.”When Rhys regained enough strength, he was transferred from hospital in south Wales to a sterile room at Great Ormond Street Doctors soon began the search for a bone marrow donor.

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